Proteomics of the post-translational modifi cations: the knowns and the unknowns

Introduction: Application of Proteomic Technologies for the Analysis of Microbial Infections

Proteomics belongs to the group of so called “ omics ” technologies that are preferentially exploited for the global analysis of temporal or conditional alterations in gene expression, on either the gene or protein level. Proteomics is focused on proteins and provides information about their abundances, post translational modifi cations, localization and mutual interactions. Current proteomic p...

Kinematic and Dynamic Analysis of Tripteron, an Over-constrained 3-DOF Translational Parallel Manipulator, Through Newton-Euler Approach

In this research, as the main contribution, a comprehensive study is carried out on the mathematical modeling and analysis of the inverse kinematics and dynamics of an over-constraint three translational degree-of-freedom parallel manipulator. Due to the inconsistency between the number of equations and unknowns, the problem of obtaining the constraint forces and torques of an over-constraint m...

High-Tc Superconductivity: Known Knowns and Unknowns

Known knowns, known unknowns, unknown unknowns and unknown knowns in DNA barcoding: a comment on Dowton et al.

RUPERT A. COLLINS1∗ AND ROBERT H. CRUICKSHANK2 1Laboratório de Evolução e Genética Animal, Departamento de Biologia, Universidade Federal do Amazonas, Av. Rodrigo Otávio, Manaus, Amazonas, Brazil and 2Department of Ecology, Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln 7647, Canterbury, New Zealand ∗Correspondence to be sent to: Departamento de Biologia, Universidade Fed...

Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps

than a decade since their discovery, neutrophil extracellular traps (NETs) remain in the headlines. Initially, interest focused on the structure of extracellular NET chromatin and its capacity to capture and damage bacteria. Soon, however, researchers began to see the impli cations of extracellular chromatin for the development of autoimmune diseases. One quintessential auto-immune disease, sys...